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Bromodomain containing protein 4 (BRD4) regulates expression of its interacting coactivators in the innate response to respiratory syncytial virus

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Bacterial products such as LPS, predominantly derived by gramnegative organisms, can activate microglia TLR4 [214, 215], enhancing syn uptake, oxidative stress, and cytokine productionall contributing to neurotoxicity [216, 217, 218]

Close environment and asthma pathogenesis Recent researchers have proposed that environmental exposures can significantly influence the phenotype of allergic diseases, including asthma (57)

Wibbenmeyer LA, Morgan LJ, Robinson BK, Smith SK, LewisKealey RWGP (1999) Our chemical burn experience: exposing the dangers of anhydrous ammonia

Despite the extensive accumulation of evidence and proposal of multiple pathogenic mechanisms, there is much to learn about how these disorders develop and progress