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In its simplest form, the mechanism of AR action entails that androgen binding activates AR to execute a specific transcriptional program that controls CaP growth and progression (Fig

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Paepalantine (9,10-dihydroxy-5,7-dimethoxy-1H-naptho(2,3c)pyran-1-one) is an isocoumarin previously isolated from the capitula of the Brazilian endemic Paepalanthus bromelioides