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Their unique ability to navigate through the biological system, transport important biomolecules, and influence the pathophysiology in the recipient cells make exosomes an attractive candidate for biological and biopharmaceutical research 22,23,24

1,4-Bipiperidine-1-carboxyclic acid, 3-hydroxy-8-apo-E-caroten-8-al, cyclo(L-Trp L-Pro), heptanal, 2-benzylidene-(E), leucine proline dipeptide, meconin, and SHCHC (2-succinyl-6-hydroxy-2,4-cyclohexadiene-1-carboxylate, precursor of vitamin K) were detected only for anaerobically cultured bacteria (Supplementary Table S4)

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Using the Broad Institute's Connectivity Map (cMap), a database that profiles gene expression changes produced by thousands of bioactive molecules, Pickart and Vasquez-Soltero identified that GHK-Cu influences the expression of more than 4,000 human genes

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