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The ability of hydroxocobalamin to rapidly scavenge and detoxify cyanide by chelation has resulted in several acute animal and human studies using systemic hydroxocobalamin doses at suprapharmacological doses as high as 140 mg/kg to support its use as an intravenous (IV) treatment for cyanide exposure

D: Appl

The cell cycle: a key to unlock EZH2-targeted therapy resistance

Siemers, E

The therapeutic effect of asiaticoside on cerebral ischemiareperfusion injury may involve more mechanisms, which is worth further exploration to enrich the pharmacological mechanism of asiaticoside and lay a foundation for its clinical application

According to reports in the literature, islets that account for only 1% of the total pancreatic mass receive about 10%15% of arterial blood (15), which indicates that the amount of O 2 per islet volume that is transported by hemoglobin is much larger than that of another pancreatic parenchyma