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Scoditti, E

So, this is playing a role in the development of diabetes even though its playing a role in normal healthy metabolism

Tomer Y (2014) Mechanisms of autoimmune thyroid diseases: from genetics to epigenetics

The fact that the best-fitting model was quadratic rather than strictly linear is itself informative: it suggests that pushing the dose to 6.0 mg did not buy additional histologic benefit and may have shifted the tolerability balance, exactly the kind of nuance a dose-finding trial exists to surface