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In the DRIVE-SHIFT clinical trial of virologically suppressed adults who switched to once-daily DOR/3TC/TDF, slight weight gain consistent with the weight gain expected in people without HIV was observed although approximately 40% of individuals lost weight or had no change in weight through 144 weeks [20]

These lipid lowering drugs, also known as HMG-CoA-reductase inhibitors, form the cornerstone for prevention and treatment of cardiovascular disease

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