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GSH deficiency is associated with a number of central nervous system diseases such as Multiple Sclerosis, Autism, Bipolar disease, Alzheimers, and Parkinsons disease

NE is also involved in regulating attention [86], in particular those related to emotional and neutral emotions [87], and this signalling network has been found altered in different brain areas in patients with ADHD [88]

It was found that the combination of BDNF and FGF1 significantly protected SGNs after 4 or 8 weeks of aminoglycoside treatment, although the effect at 8 weeks appeared to be relatively weak [132]

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