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Lifestyle factors such as smoking, excessive alcohol consumption, poor diet, and obesity are also major contributors to oxidative stress ( In conclusion, ROS play a dual role in sperm function, being essential for processes such as capacitation, motility, and fertilization at physiological levels, but harmful when produced in excess

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Most cells in the rest of the body are believed to acquire iron from plasma transferrin (an iron-protein chelate), via specific transferrin receptors and receptor-mediated endocytosis (Klausner, et al, 1983)

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PMID: 24286351