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Notable tumor-related immune checkpoint molecules include PD1, CTLA4, Tim3, and LAG3, with PD1 and CTLA4 being the most extensively studied [18]

Another organ in the rat contrasting with the situation in the penis is the rat testis where AR concentration increases during sexual maturation,19 although this appears to occur because of the similar increase in Sertoli and Leydig cell numbers

To view a copy of this licence, visit About this article Cite this article Xiong, QW., Liu, Y., He, M