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In vitro studies with human hepatocytes showed that phenytoin and phenobarbital inhibit acetaminophen glucuronidation, suggesting that other pathways of the drug metabolism, like oxidation to toxic NAPQI, may be potentiated [17,18]

Chapter 17 - extrinsic sensory afferent nerves innervating the gastrointestinal tract in health and disease in Physiology of the Gastrointestinal Tract