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A Chinese group treated 34 patients who had failed previous CD19-targeted CAR T-cell therapy with CD22-targeted CAR T cells.[205] CR occurred in 80% of the patients evaluable at day 30 (71% of all patients)

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PMID: 40222577

In all dosing groups except the pegIFN group, at least one patient experienced an HBV DNA increase (Fig.1A and B)

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Gene set enrichment analysis (GSEA) indicated that vitamin D reversed ozone-driven pathways related to inflammation, oxidative stress, and immune dysfunction