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It is notable that high AR activity, rather than high AR expression per se, has been identified as a predictive biomarker of response to this treatment and transcriptional downregulation of AR has emerged as a mechanism of resistance to HD androgens in a subset of patients 33

The study has some limitations

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In oviparous chickens, post-hatching nutrients, which include energy, protein, amino acids (AAs), vitamins, fatty acids, and exogenous plant extracts, are derived primarily from the diet

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