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Additionally, serum was collected right before injection, every 30 minutes the first 6 hrs post-injection, as well as at 24 hrs post-injection

DWI showed highsignal lesions along the corticomedullary junctions, and fluidattenuated inversion recovery (FLAIR) imaging showed subcortical WM hyperintensities

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Therapeutic Strategies and Future Directions Despite the progress that has been made in understanding the molecular mechanisms underlying mitochondrial diseases, there are currently no specific treatment options for LS and other related mitochondrial disorders