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Targeting these CD38-expressing cells may help restore immune responses against tumor cells

a single dose methylcobalamin of 1500 mcg in patients with peripheral neuropathy

However we recommend strict monitoring of these patients

IGF-1 LR3 mimics insulin-like growth factor, aiding muscle repair and protein synthesis

The killing effect of CD38 mAbs on CD38 high NK cells should be minimized and the potential combination of CD38 low/- NK cells and CD38 mAbs should be maximized to better benefit from their therapeutic efficacy against MM