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De Wever, O

To eliminate monophenolase activity, double mutations targeting the 1 st and 2 nd activity controllers were designed (Asn240Lys/Leu244Arg and Asn240Thr/Leu244Arg)

Elevated ROS injure cells by promoting degradation of cellular proteins, lipids and DNA, subvert beta cell biosynthetic capacity and cause endoplasmic reticulum (ER) stress or entwine with it (Hasnain et al

glutathione inhibitors

Using ThiolTracker Violet we discovered that thiols are abundant in, and largely localized to, the cytoplasm of syncytia induced by H

The advantage of a polymeric microsphere matrix lies in its ability to protect the loaded drug from enzymatic and chemical degradation