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J Biol Chem 281(9):58615868 Sugahara KN, Murai T, Nishinakamura H, Kawashima H, Saya H, Miyasaka M (2003) Hyaluronan oligosaccharides induce CD44 cleavage and promote cell migration in CD44-expressing tumor cells

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That is not a dismissal genuine, reproducible preclinical findings and real ophthalmic trials sit inside this story, and they are worth understanding

Jeon BN, Yoo JY, Choi WI, Lee CE, Yoon HG, Hur MW