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The results of the MTT assay were consistent with the results of LDH assay as CuCl 2 and Cu(OAc) 2 were able to induce significant cytotoxicity in the HaCaT keratinocytes within 24 hours, but not for GHK and GHK-Cu

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MOTS-c (10 mg) is a mitochondria-derived peptide that activates AMPK, regulates nuclear gene expression under metabolic stress, and enhances insulin sensitivity [4][5][6]