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Mechanism of DNA methylation-mediated downregulation of O6-methylguanine-DNA methyltransferase in cartilage injury of Kashin-Beck disease

This instability of heterochromatin structure is closely associated with cancer development and could be partly repaired by histone methyltransferase SETDB1 that is specifically recruited to the UV-damaged heterochromatic regions and maintains the H3K9me3 modification on newly deposited H3 histones, helping to protect the cell from the effects of genomic instability [153]

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Ginger aids digestion and supports gut health

They say the work could provide a basis for reversing the greying process