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Levels did not significantly differ between those mothers who, according to a dietary questionnaire, took vitamin supplements containing B 12 compared to those who did not, although the B 12 supplemental dose was only 3 mcg per day.[45] Four hundred ninety-one pregnancy women in Dar-es-Salaam, Tanzania were randomized to receive a daily multivitamin supplement containing 50 mcg vitamin B 12 or placebo from 20 weeks gestation

The elevated concentration provides enhanced therapeutic effects through increased growth factor expression, accelerated angiogenesis, and more robust anti-inflammatory action

He serves as principal investigator for numerous national cooperative group and institutional clinical trials