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Its unusually high acidity, i.e., the ease with which the C-2 proton dissociates, is due to the presence of the quaternary nitrogen in the thiazolium ring, a positively charged atom capable of stabilizing the resulting carbanion by electrostatic attraction

Representative images of Prussian blue staining of indicated E12.5 whole embryo sections (bottom)

The procedure was approval by the Ethics Committee of the Medical Science Research of Affiliated Hospital of Jining Medical University (No

In SURMOUNT-1, tirzepatide produced large average body-weight reductions over 72 weeks, with higher doses associated with greater weight loss

Chu YT, Wang YH, Wu JJ, Lei HY

Blood 136 (20), 23462358