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Future studies should be done prior to determining the translatability of the current work to cholangiopathies, including evaluation of NAC treatment in WT mice, evaluating NAC potential toxicity, along with further age time points of treatment and potentially optimization of NAC delivery to the EHBD

The uniqueness of GHK is that it may allow simultaneous resetting of multiple genes to target an array of various biochemical pathways to increase resistance to cancer and reverse pathological epigenetic changes in cancerous cells

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The aforementioned observations prompt the question of whether NF-B directly regulates EAAT3 expression at the transcriptional level

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