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As a drug delivery system, nano gels have several advantageous features for the PD, like high drug loading capacity, biocompatible nature, and safeguarding the encapsulated drugs from degradation (137, 138)

In brief, the primers GDF15A 5-TCAACTTTAAGCCAGAAGGTGGCG-3, GDF15B 5-CTTCGGGGAGACCCTGACTCAGC-3 and GDF15D 5-ACTGCGAATCTAGAGAACCCTGAC-3 were used to amplify the targeted region

5.8%, P = 0.554)

Likewise, no injuries and infiltration of inflammatory cells were observed in H&E-stained sections of major organs isolated from maternal rats and fetuses (Supplementary Fig

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10.1136/bmjopen-2018-025884 210 TenreiroL.AlvesS.AlvesP