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Research suggests that long-term exposure to antibiotics can damage the quantity and diversity of distal gut microbiota, even in the absence of clinically related gastrointestinal symptoms

Additional published animal studies indicate that acetaminophen exposure in utero adversely impacts reproductive capacity of both male and female offspring at clinically relevant exposures [see Nonclinical Toxicology (13.1)]

VenkateshBFinferSCohenJRajbhandariDArabiYBellomoRet alAdjunctive glucocorticoid therapy in patients with septic shock

doi: 10.1084/jem.20211141 303 LiHLiuYLiuYXuLSunZZhengDet al

doi: 10.1093/emph/eoz024