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Discard any remaining solution after that, even if the vial still has liquid in it

2008) adapted to a microplate reader (PMID: 32218124)

Upon ingestion, caffeine readily crosses the blood-brain barrier and blocks adenosine receptors , an effect responsible for many of its pharmacologic actions

The following covariates were adjusted in the model: child sex, delivery type, parity, gestational age, birth weight, maternal age, maternal marital status, prenatal smoking, prenatal alcohol use, intrauterine inflammation, preeclampsia, diabetes mellitus, maternal stress, estimated cell-type proportions (CD4 + T cells, CD8 + T cells, B cells, monocytes, granulocytes, natural killer cells and nucleated red blood cells) and surrogate variables