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However, improper operation can lead to side effects such as vascular occlusion, blindness, nodules, granulomas, delayed hypersensitivity reactions, and poor cosmetic results [300]

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doi: 10.3389/fphar.2022.1089130 Received 03 November 2022 Accepted 07 December 2022 Published 19 December 2022 Volume 13 - 2022 Edited by Xin Wang, Hokkaido University, Japan Reviewed by Jesus Osada, University of Zaragoza, Spain Dharmani Devi Murugan, University of Malaya, Malaysia Updates Copyright 2022 Garca-Berumen, Vargas-Vargas, Ortiz-Avila, PiaZentella, Ramos-Gmez, FigueroaGarca, Meja-Zepeda, RodrguezOrozco, SaavedraMolina and Corts-Rojo

Lipoedema is often classified as having five types and four stages