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Eucaryotic isoenzymes are typically membrane-associated and localized in the endoplasmic reticulum membrane or the mitochondrial inner membrane [11]

A 30-minute chlorine gas challenge (184 ppm or 400 ppm) significantly induced hypoxemia and hypercapnia, increased BAL fluid protein concentration, and significantly decreased BAL fluid ascorbate levels in a rat model (Yadav et al., 2010)

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Nat Rev Genet 13:358369 Prot JM, Briffaut A-S, Letourneur F, Chafey P, Merlier F, Grandvalet Y, Legallais C, Leclerc E (2011) Integrated proteomic and transcriptomic investigation of the acetaminophen toxicity in liver microfluidic biochip

This structural and functional damage ultimately leads to male infertility [105]

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