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PCLS and in vitro analysis of pHSCs, pHHs, and Huh7 cells (including mono and co-culture models (spheroids)) also showed that YAP-related and profibrotic genes were upregulated when exposed to HIV

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Taken together, these advanced organoid-based models are expected to close the knowledge gap of human embryo implantation, enabling breakthroughs in the study of female infertility