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Untreated pain provokes myriad unwanted physiologic responses such as anorexia, self-trauma, central sensitization and maladaptive behaviors, all of which prolong recovery and add unnecessary stress

doi: 10.1186/s12891-020-3159-y 284 ZhaoWLiDSuYZhaoHPangWSunYet al

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[email protected] This article was submitted to Neuropharmacology, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Hepatic Dosing for pediatrics The use of this drug is contraindicated for the treatment of juvenile idiopathic arthritis

Supervision is also important if you are managing chronic illness or recovery after infection