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Pairs of females and males were matched at a 1:1 ratio, designating the presence of a vaginal plug as gestation day (GD) 0.5

J Clin Endocrinol Metab 2003

Accordingly, the downregulation of MMP-1, MMP-3 and MMP-13 expressions and the upregulation of TIMP-1 expression were reported due to the use of TQ in chondrocytes and cartilage in the animal model