melanotic in situ Atypical junctional melanocytic hyperplasia (AJMH) and melanoma Acral lentiginous melanoma in situ:

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Data must be structured and interpretable to support confident decision-making

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For example, indoleamine 2,3-dioxygenase 1, which catabolizes tryptophan, results in immune tolerance by activating Tregs, deactivating effector T cells, and inducing immune cell apoptosis