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Interestingly, BDNF signaling through inhibition of oxidative stress prevents glutamate-induced neurotoxicity in PD and the final phase of amyotrophic lateral sclerosis (ALS) (Jin, 2020

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47,48 However, notably, recent findings in FitzGeralds group showed that the most commonly applied LC-MS/MS approach to SPM detection has been shown to be fundamentally flawed, especially in the analytical methods and experimental conclusions