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Affiliation: 1 Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy ORCID: Affiliation: 2 Corporate Preclinical R&D, Chiesi Farmaceutici S.p.A., 43122 Parma, Italy ORCID: Affiliation: 1 Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy ORCID: Affiliation: 2 Corporate Preclinical R&D, Chiesi Farmaceutici S.p.A., 43122 Parma, Italy ORCID: Affiliation: 1 Department of Medicine and Surgery, University of Parma, 43126 Parma, Italy ORCID: Affiliation: 2 Corporate Preclinical R&D, Chiesi Farmaceutici S.p.A., 43122 Parma, Italy Email: [email protected] ORCID: Explor Med