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Cytokine release syndrome is one of the safety concerns associated with this novel treatment approach [45, 50]

10.1371/journal.pone.0130908 111 QiuY.XuS.ChenX.WuX.ZhouZ.ZhangJ.et al (2023)

Controlled and Targeted Delivery: Liposomes also provide for controlled and targeted drug release with the highest degree of control

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Similarly, metallic nanoparticles (MNPs) (gold, silver, zinc oxide) are conjugated with phytoextracts like Aloe barbadensis , Leucas aspera , Pyrenacantha grandiflora , and Withania somnifera for wide therapeutic efficacy against microbial infections, ulcerative colitis, cancer, and oxidative stress by facilitating extended drug circulation, intercellular targeting, drug stabilization, and higher delivery [19, 20]

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