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2.3.1 Sestrin2 Sestrin2, a highly conserved protein belonging to the Sestrin family, is involved in multiple biological functions, including regulating redox reactions, metabolic homeostasis, and the aging process (Lee et al., 2013

[10] [3] Since previous research by Christiane Nsslein-Volhard and Eric Wieschaus (which won them the Nobel Prize in Physiology or Medicine in 1995) had already established the function of Wg as a segment polarity gene involved in the formation of the body axis during embryonic development, researchers determined that the mammalian int1 discovered in mice is also involved in embryonic development

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