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doi: 10.1038/s41418-020-00719-2 189 ZhangLHanJWuHLiangXZhangJLiJet al

From an immunological perspective, these associations arise from a breakdown in self-tolerance mediated by overlapping T-cell and B-cell autoreactivity, shared cytokine pathways (e.g., IFN-, IL-18), and common antigen-presenting HLA alleles

The problem is that strongest evidence base here means rats and cell cultures

Cardiovascular toxicology

Omega-3s support cardiovascular health, brain function, and the body's inflammatory response

Uridine alleviating the need to increase mitochondrial biogenesis led us to conclude that increased pyrimidine salvage (probably via UCK2) is driving this mitochondrial adaptation