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GSH depletion can enhance oxidative stress and may increase protein aggregation leading to initiate cell death in distinct neuronal populations

Proellex (telapristone) In 2002, Attardi et al 143 examined the in vitro properties of one of the compounds synthesized by the US-NIH (code name CDB-4124), later named as proellex, or telapristone, and its mono-de-methylated metabolite, code named CDB-4453