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Further, we also determined the effect of Glu supplementation on monoaminergic neurotransmission in brain and found that Glu supplementation enhances concentration of NA, DA and 5-HT via affecting their metabolism in brain

Anti-inflammatory and antioxidant properties derived from dietary components such as carotenoids and polyphenols, which are commonly found in fruits and vegetables, may improve metabolic profiles, mitigate oxidative damage, and counteract the formation of AO and tau aggregates, particularly in elderly individuals [73]

Apparent mineralocorticoid excess syndrome arises when 11-hydroxysteroid dehydrogenase type 2 is deficient, allowing cortisol to activate mineralocorticoid receptors inappropriately and drive severe hypertension

This analysis aims to further elucidate the mechanisms underlying BIPN development (Figure 2)

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W., Dee, M