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While clinical trials confirm curcumins safety and efficacy at appropriate dosages for various human and animal diseases, its clinical utility is hindered by poor bioavailability due to limited absorption and rapid metabolism

Geller et al., 1993

The NAD+ IV drip is administered slowly to ensure comfort and optimal absorption

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Patients with simple steatosis who have not yet progressed to MASH lack approved pharmacological options, and current clinical management primarily depends on lifestyle modification, which is often limited by poor adherence and inconsistent therapeutic outcomes

Molecular dockings were performed on AutoDock Vina 1.2.0 software and CB-DOCK2 website 60,61