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The combination arm was terminated early due to severe adverse events and deaths, while NAC alone showed no significant effect on lung function, though secondary endpoints (6MWD, QoL) improved modestly (139)

In addition, in LPS-induced Caco-2 cells, Paeoniflorin restored the expression of TJ proteins such as claudin-5 and occludin and reduced the permeability of the intestinal epithelium by activating the Nrf2/HO-1 signaling pathway (Wu et al., 2019)

The intracellular Salmonella were enumerated based on their respective antibiotic resistance profiles

With nano-formulations acting as a nanocarrier with antidiabetic and antifungal activity among the most prevalent fungus species, this strategy would significantly decrease the probability of infections associated with diabetic patients

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Results: Experts agreed that NAC is useful as an adjunct in COPD especially chronic bronchitis phenotypes mainly for preventing exacerbations at 600 mg twice daily