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Weighing such small amounts to create 10mLs or even 20 mLs of sample for the standards was difficult and even beyond the sensitivity of the mg balance (10mLs of a 100uM Niclosamide solution requires weighing 0.327mgs)

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In addition, the neurotoxic effects of homocysteine may also play a role in the neurologic and psychiatric disturbances that are associated with folate and vitamin B12 deficiency. A

Journal of Neurochemistry , 114(3), pp.820831