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After GSH donates its electron, it becomes oxidized and leads to the formation of glutathione disulfide (GSSG)

However, on day 30, group 1 indicated elevation in the activity of CAT (5.130.36 U/mg protein), whereas on day 30, the activity of CAT in group 2 further declined and was recorded as 4.910.55 U/mg protein

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Di Giandomenico S, Frapolli R, Bello E, Uboldi S, Licandro SA, Marchini S, et al

ABCC5 facilitates the acquired resistance of Sorafenib through the Inhibition of SLC7A11-induced ferroptosis in hepatocellular carcinoma