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Retrieved July 16, 2025, from Madison Family Care

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10.1371/journal.pone.0248521 29 HuangD

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It is critical for maintaining DNA stability and synthesis (Wang et al., 2018) and supports processes such as apoptosis and autophagy, crucial for removing damaged cells and maintaining cellular health (Mao et al., 2023), improve cardiovascular health (Wu et al., 2022), and enhance cognitive functions (Pekar et al., 2021)

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NNMT is an enzyme that methylates nicotinamide, a key NAD+ precursor, depleting cellular methyl donor pools and influencing both NAD+ availability and broader methylation pathways

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Soluble epoxide hydrolase gene deletion improves blood flow and reduces infarct size after cerebral ischemia in reproductively senescent female mice

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