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BNIP3 mediates the different adaptive responses of fibroblast-like synovial cells to hypoxia in patients with osteoarthritis and rheumatoid arthritis

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The pathogenesis of CIPN is multifactorial, involving oxidative stress, neuroinflammation, neurotrophic factor depletion, and mitochondrial dysfunction (610)

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Despite the important and complex role collagen crosslinking plays in tendon formation and pathology, it is less clear how these crosslinks are regulated