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Description

Furthermore, a nonlinear relationship and threshold effects of TMAO were found for MACEs in CAD and CAD-DM patients, with TMAO turning points of 318.28 ng/mL and 371.59 ng/mL, respectively

Moreover, mRNA abundance of SREBP-1c , acetyl CoA carboxylase 1 ( ACC1 ) and fatty acid synthase ( FAS ) decreased in the CPE group compared to the CON group, while mRNA abundance of PPARA , acyl-CoA oxidase ( ACO ), carnitine palmitoyltransferase 1 A ( CPT1A ), glucose-6-phosphatase ( G6P ) and phosphoenolpyruvate carboxykinase ( PEPCK ) increased (Fig