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by adjusting pressure, temperature, and the use of co-solvents such as ethanol or water, it can be optimized for higher purity and targeted extraction of diverse phenolic compounds (59)

The primary outcome is pre-MT recanalization, defined as reperfusion in over 50% of the affected area or no retrievable thrombus on initial digital subtraction angiography

Crucial role of the aryl hydrocarbon receptor (AhR) in indoxyl sulfate-induced vascular inflammation

All authors reviewed, read and approved the manuscript

Otherwise, bile duct-ligated rats commonly presented intracranial (superior sagittal sinus), portal and caval hypertension and aortal hypotension, gross brain swelling, hemorrhage and lesions, heart dysfunction, lung lesions, liver and kidney failure, gastrointestinal lesions, and severe arterial and venous thrombosis, peripherally and centrally

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