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While this condition is best known for how it affects muscle control, balance and movement, it can also cause a wide range of other effects on the senses, thinking ability, mental health and more

10.1002/ana.22052 83 Garca-CasaresN.Gallego FuentesP.BarbanchoM.Lpez-GigososR.Garca-RodrguezA.Gutirrez-BedmarM

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2 These include: A ME/CFS-like phenotype with post-exertional malaise and impaired bioenergetics A dysautonomia/POTS-dominant presentation A mast celldriven inflammatory phenotype Persistent cardiopulmonary injury This heterogeneity explains why a single treatment approach fails

Reciprocally, gut microbiota biotransform dietary components to produce various physiologically active metabolites, such as SCFAs, secondary bile acids, and indole derivatives, which enter the liver via the portal venous system and participate in host glucose and lipid metabolism as well as immune regulation ( The concept of the gut-liver-kidney nutritional metabolic axis has gradually emerged and received widespread attention in recent years