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In obesity and metabolic dysfunction, NNMT is often overexpressed in adipose tissue, depleting nicotinamide and lowering NAD+ availability [2]

Results Plasma L-Cn Levels Are Elevated in Chronic HBV Infection and HBV-Related HCC but Decreased in HBsAg Loss Firstly, we attempted to evaluate the plasma L-Cn status of patients with chronic HBV infection ( Table 1 )

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Petri et al, 1996