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J.BieriP.LeibundgutM.LeitnerA.AebersoldR.BoehringerD.et al

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they have an inactive copy of the TMLHE gene, which is located on the X chromosome

It first reacts to this by reducing muscle mass (only later does it also attack fat reserves)

Skin and coat appearance are also shaped by broader nutrition and barrier support, not single ingredients (HAE, 2024)