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Besides, Nrf2 plays essential roles in metabolism regulation (e.g., glucose metabolism), and the metabolites produced in these processes including NADPH and GSH, help maintain redox balance

Antineoplastic efficacy of melphalan and N-(2-chloroethyl)-N-nitrosocarbamoyl--lysine, in combination with diazoxide or insulin in autochthonous mammary carcinoma of the Sprague-Dawley rat