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doi: 10.2174/1570159X20666220222150811 44

FSP1 can inhibit ferroptosis by reducing ubiquinone or CoQ to ubiquinone or CoQH 2 on the cell membrane, with the latter functioning as an antioxidant that trap radicals and thus prevents lipid peroxidation, thereby preventing ferroptosis (Fig

In addition, RvE1 demonstrated synergistic effects with statins in several AS models, markedly reducing proinflammatory cytokine levels, inhibiting foam cell formation, and delaying vascular calcification

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Wu C, Pan LL, Niu W, Fang X, Liang W, Li J, et al